Endocrine Abstracts

Impaired glucoregulation is an important factor in the development of coronary heart disease. Numerous studies have reported a significant incidence of undiagnosed glucose intolerance in patients with coronary heart disease.Aim: The aim of our study was to compare the utility of HbA1c versus oral glucose tolerance test (GTT) in detecting glucose tolerance abnormality in patients with coronary heart disease admitted for elective coronarography.<p clas...

Background: Optimal testing of beta-cell dysfunction is still elusive. Oral based solid-food tests could superiorly approximate real-life stimulation by incorporating incretin activation. Increased body fat was recently associated with better preserved beta-cell secretory response, due to gluco-lipotoxicity induced adaptation.Objective: To assess C-peptide response to standardised test meal (STM) and its dependency on subject characteristics in newly dia...

Background: Vascular complications are leading cause of increased morbidity and mortality of diabetic patients. Pathophysiological mechanisms included in the development and progression of diabetic complications are various and lately it has been postulated that matrix metalloproteinases MMP-2 and MMP-9, zinc-dependent endopeptidases through remodeling of extracellular matrix can contribute to the onset and progression of diabetic vascular complications. The aim of our study w...

Abdominal obesity and metabolic syndrome are known to increase in prevalence from premenopause to postmenopause in women. Both are well recognized predictors of cardiovascular disease and diabetes in women.The objective of this study was to assess the presence of obesity and metabolic syndrome during the menopausal transition in women from Serbia.Methods: Our results present a part of the National epidemiological cross-sectional st...